Graduate Courses BIOE 2810

BIOE 2810 - Biomaterials and Biocompatibility

Instructor: Wagner

Credits: 3

Term: Spring

Description: This course serves as an introduction to biomaterials and biocompatibility and assumes some background in organic chemistry and biology. The first half of the course connects material chemical properties to performance issues relevant to biomaterial applications. The second part of the course introduces biocompatibility issues as they follow from protein adsorption. Thrombosis, inflammation, and infection are of primary interest. Throughout the course ties are made between the topic of study and clinically relevant material and device performance.

Prerequisites: Introductory Biology, Organic Chemistry, Physiology. Engineering Background. Biochemistry, Molecular Cell Biology, and Immunology would be very helpful, but are not essential.

Required Texts: Biomaterials Science: An Introduction to Materials in Medicine, edited by Ratner BD, Hoffman AS, Schoen FJ, Lemons JE, New York, Academic Press, 1996.

Course Objectives: Upon completing this course, students should: understand the basic principles behind human tissue response to artificial surface implantation, be familiar with the general types of polymeric, metallic, and natural materials used in soft and hard tissue replacements, drug delivery devices, and extracorporeal devices, understand techniques utilized to control the physiologic response to artificial surfaces, be able to critically review the current biomaterials literature and be acquainted with current research in the field, and be able to evaluate the design criteria which a material must meet for a given biological application and understand what is required for "biocompatibility".

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Syllabus: Microsoft Word Format

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