Graduate Courses BIOE 3002

BIOE 3002 - Advanced topics in Biosolid mechanics

Instructor:

Michael S. Sacks, Ph.D.
Department of Bioengineering
Room 742 Benedum Hall
Tel: 624‐8985
email: msacks@pitt.edu

Main office:
100 Technology Drive
Room 234
Tel: (412) 235‐5146

Credits: 3

Term: Fall

Overview: This is an advanced graduate course that the application of biosolid mechanics to describe the mechanical behavior living structures. The course will be separated into the following:

1. Fundamental concepts:
   a. Kinematics, Stress, Strain
   b. Balance principles, objectivity
   c. Hyperelastic materials
2. Biological applications.
   a. Mechanical properties of specific tissues, (e.g. tendon, muscle, heart, vascular)
   b. Growth and remodeling using mixture theories.
   c. Approaches used to model cells (e.g. blood cells, myofibroblasts).

Prerequisites: Continuum Mechanics or equivalent, BioE 2064 or equivalent.

Office hours: All office hours will be held in Room 742 Benedum Hall.

Texts:
Required:
1. “Non‐linear solid mechanics – A continuum approach for engineering” by Gerhard A. Holzapfel, Wiley, 2000.

Highly recommended:
1. “Cardiovascular Solid Mechanics” by J.D. Humphrey. Published by Springer‐Verlag, 2001
2. “Introduction to Continuum Mechanics” by Lai, Rubin, and Krempl, Butterworth‐Heinemann, 1999 (This may be available as PDF file – stay tuned).
3. “Continuum Mechanics” by A.W. Spencer (This is out of print, so see me for a free copy).
4. “Biomechanics: Mechanical Properties of Living Tissues” by Y.C. Fung, published by Springer‐Verlag, 1993.

Homework assignments: Homework will be assigned on a regular basis and due as listed on the schedule at the beginning of the lecture, unless otherwise noted. Homework assignments are the key method of assessment in this class, as there are no in‐class tests.

Exams: There will be no in‐class exams.

Term paper: Each student will be required to write a detailed 15 page detailed written report of a topic of your choice.

Grading: Homework will count as 75% of your grade, and 25% from the presentation/report.